Leidos Biomedical Research, Inc.
Operating the Frederick National Laboratory for Cancer Research
A 25 year partnership in biomedical innovation
For more than 25 years, Leidos Biomedical Research has partnered with the National Cancer Institute (NCI) to operate Frederick National Laboratory for Cancer Research, the only National Laboratory focused exclusively on biomedical research.
Our work is dedicated to improving human health and enabling scientists to conduct investigator-initiated, hypothesis-driven research. Our team provides expertise in genetics, genomics, protein science, proteomics, bioinformatics, high-performance biomedical computing, and clinical operations. We provide scientific support to the NCI, the National Institute of Allergy and Infectious Diseases, and many more of the National Institutes of Health’s 27 institutes and centers, collaborating with intramural and extramural investigators to accelerate discovery and innovation in the biomedical sciences. Our focus is on cancer, HIV infection, and emerging infectious diseases such as COVID-19.
Our commitment to this unique partnership is on display through our work with government agencies, organization directorates and academic/extramural institutions that routinely come together to solve the world’s most critical biomedical challenges. We are proud of this partnership and the contributions we have made to advance biomedical research and health over the past 25 years.
Critical research for global public health challenges
Advancing Cancer Research and Understanding
Our biomedical informaticists advance disease research using high-performance computing, data science, artificial intelligence, and machine learning. Examples of their work include transforming drug discovery through ATOM, creating virtual models with Digital Twins and accelerating cancer research with JDACS4C and the Cancer Moonshot.
Advancing nanotechnology in cancer therapeutics
Through our work with the Frederick National Laboratory, we operate the National Cancer Institute's Nanotechnology Characterization Laboratory, a public-private partnership to advance science and expedite promising nanotech therapies and diagnostics. Our scientists accelerate the development of nanotechnology-based products for cancer patients, reduce risk, and encourage private-sector investment in technology development.
Advancing scientific insights of cancers driven by RAS mutations
One-third of human cancers are driven by mutations in the RAS family of genes. Through our work with the National Cancer Institute’s RAS Initiative, we facilitate an international RAS research community, search for an effective RAS inhibitor and our scientists investigate approaches to RAS-driven cancer from protein production to assay development.
Access to high-resolution imaging
Advances in microscopy technology, as well as improved computational methods for analyzing single-particle cryo-EM data has led to a revolution in cancer research. The National Cancer Institute's National CryoEM Facility (NCEF) is located at the Frederick National Laboratory, where our microscopists meet the needs of cancer researchers in academic labs and provide state-of-the-art cryo-EM services.
Conducting data science and biomedical research in the global effort to combat COVID-19
The National Cancer Institute, in partnership with the National Institute of Allergy and Infectious Disease and 25+ government organizations and biomedical research institutions, established the Serological Sciences Network, (SeroNet), the nation’s largest coordinated effort to study the immune response to COVID-19. Through SeroNet, our employees pivoted the Frederick National Laboratory's HPV Serology Lab to support COVID-19 serology. In addition, our teams facilitated randomized, placebo-controlled international clinical trials, worked to explain genetic susceptibility to COVID-19, and leveraged the RAS Initiative compound libraries to screen for novel candidate agents to combat the disease.
World-class scientific talent
Our experts are committed to solving the world’s most critical public health challenges, driving scientific discoveries and biomedical advancements. Meet some of our Leidos Biomedical Research team!
Learn more about our work
Frederick National Laboratory is one of 18 national laboratories, and the only one dedicated to biomedical sciences. Our work creates a culture that empowers employees, sparks innovation, and addresses the most urgent challenges in biomedical research.